**American Journal of Nursing (AJN) Book of the Year Awards, 2nd Place in Advanced Practice Nursing, 2025**
**Selected for 2026 Doody’s Core Titles as an Essential Purchase in Advanced Practice**

Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and Physician Assistants, Third Editionbuilds on the same foundation of clearly explained, up-to-date, and clinically current content as Lehne’s trusted undergraduate text, while focusing on the information that advanced practice nurses and Physician Assistants specifically need for safe and effective prescribing. Introductory chapters provide foundational content in the areas of prescriptive authority, rational drug selection, prescription writing, and promoting positive outcomes of drug therapy. Core drug chapters focus on the drugs that you will most commonly see in clinical practice. Pharmacotherapeutic decision-making is emphasized, with Black Box Warnings and new Drug Decision Guide boxes. This edition features completely updated content with new chapters on drugs for sexual dysfunction and drugs for transgender health. It’s everything you need to be a safe and effective prescriber!
UPDATED! Content throughout reflects the latest drug information and evidence-based treatment guidelines and protocols
NEW! Drugs for Sexual Dysfunction and Drugs for Transgender Health chapters in a newly combined Reproductive Health unit promote health equity
NEW! Drug Decision Guide boxes for selected drugs emphasize a rational process for drug selection
NEW! Clinical Pearls boxes highlight expert tips for rational drug prescription
NEW! Chapter-opening Evolve links and “Top 300” drug icons throughout identify drugs that appear on the Top 300 prescribed drug list to help you focus your study time
ENHANCED! Introductory chapters emphasize prescriber-level pharmacokinetics and pharmacodynamics content
NEW! Coverage addresses immunizations and therapeutics (e.g., Regeneron, Resdemivir, dexamethasone) for SARS-CoV-2 infection (COVID-19)
UPDATED! Enhanced coverage of sexually transmitted infections reflects the latest evidence-based guidelines
NEW! Drug content addresses medications for ectoparasite infestations
Introductory chapters tailored to the specific needs of beginning prescribers cover topics such as prescriptive authority, rational drug selection and prescription writing, and promoting positive outcomes of drug therapy
Carefully focused pharmacotherapeutics content reflects the drugs most commonly seen and used by primary and acute care prescribers, with an emphasis not on the first drug discovered or developed in each drug class, but on the agents most often used today
Chapters address primary care drugs first, as appropriate, followed by acute care drugs
Prescriber-focused pedagogical aids further reinforce the most important information for prescribers
UNIQUE! Summary of Key Prescribing Considerationsat the end of each drug chapter provides a concise summary of essential prescriber information
Coverage of interprofessional collaboration addresses the growing global emphasis on interprofessional collaboration and incorporates opportunities for interprofessional collaborative practice throughout
Integrated coverage of Canadian trade names appears throughout and is highlighted with a familiar maple-leaf icon